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Invitrogen
CD3/CD44 Antibody Cocktail, FITC, PE
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产品信息
MA1-12273
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Cocktail
类型
Antibody
克隆号
M2AB, 7F1
抗原
human thymocytes and TCR-gamma epsilon thymocytes
偶联物
FITC , PE
FITC , PE
FITC , PE
形式
Liquid
纯化类型
Protein A/G
保存液
PBS with 0.2% carrier protein
内含物
0.08% sodium azide
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody is a monoclonal mixture of FITC-conjugated CD3 (clone M2AB, isotype IgG1) and PE-conjugated CD44 (clone 7F1, isotype IgG1).
靶标信息
CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CD3 epsilon; CD3d; CD3e; CD3g; CD44; CD44 antigen; CD44 molecule; CDw44; ECMR-III; ECMRIII; Epican; Extracellular matrix receptor III; FLJ18683; GP90 lymphocyte homing/adhesion receptor; HCAM; Heparan sulfate proteoglycan; Hermes antigen; HUTCH-I; hyaluronan receptor; Hyaluronate receptor; PGP I; PGP-1; PGP-I; PGPI; Phagocytic glycoprotein 1; Phagocytic glycoprotein I; sCD 44; sCD44; T-cell receptor T3 delta chain; T-cell receptor T3 gamma chain; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 delta chain; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface glycoprotein CD3 gamma chain
基因别名: CD3D; CD3E; CD3G; CD44; LHR; MDU2; MDU3; MIC4; T3D; T3E; T3G
Entrez Gene ID: (Human) 915, (Human) 916, (Human) 917, (Human) 960
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