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Invitrogen
Thimet Oligopeptidase Monoclonal Antibody (4D6)
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产品信息
MA1-16816
产品规格
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
4D6
抗原
A synthetic peptide corresponding to residues 56-72 of human thimet oligopeptidase.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1.54 mg/mL
规格
154 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.
Suggested positive control: HeLa whole cell lysate, antigen standard for THOP1 (transient overexpression lysate).
靶标信息
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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