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Invitrogen
HLA-DQ1/DQ3 Monoclonal Antibody (HL-37)
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产品信息
MA1-19143
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Pig
已发表种属
Human
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
HL-37
抗原
Burkitt's lymphoma cell line Raji.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts with extracellular polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated beta chain of DQ1), but does not react with HLA-DQ2. DQ is the isotype of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages).
Western Blot: non-reducing conditions.
靶标信息
Reacts with polymorphic determinant on human HLA-DQ1 and HLA-DQ3 molecules (recognized epitope was found on isolated b chain of DQ1), but does not react with HLA-DQ2.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: HLA class II histocompatibility antigen, DQ beta 1 chain; HLA-D; HLA-DQ; HLA-DQ-beta-1 cell surface glycoprotein; HLA-DQB1; hla-dr antigen beta chain; HLADQ; HLADQ1; HLADQ3; human leucocyte antigen; MHC Class 2; MHC class II; MHC class II antigen DQB1; MHC class II antigen HLA-DQ-beta-1; MHC class II DQ beta chain; MHC class II DQ-beta protein precursor; MHC class II DQ3.1ER protein; MHC class II HLA-DQ beta glycoprotein; MHC DQ beta protein precursor; MHC DQ-beta chain; MHC DQw1-beta surface glycoprotein; MHC HLA-D; MHC HLA-DC-beta chain precursor; MHC HLA-DQ-beta cell surface glycoprotein; MHC HLA-DQ-beta chain precursor old gene name 'HLA-DQB'; MHC HLA-DQ-beta precursor; MHC HLA-DQB1-beta protein; MHC HLA-DR-beta-1 chain; MHC HLA-DRQ-beta chain; MHC II HLA; unnamed protein product
基因别名: CELIAC1; HLA-DQB; HLA-DQB1; IDDM1
UniProt ID: (Human) P01920
Entrez Gene ID: (Human) 3119
adaptive immune response
immune system process
peptide antigen assembly with MHC class II protein complex
antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
immune response
humoral immune response
antigen processing and presentation
antigen processing and presentation of exogenous peptide antigen via MHC class II
positive regulation of immune response
T cell receptor signaling pathway
positive regulation of T cell activation
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