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Invitrogen
HLA-ABC Monoclonal Antibody (MEM-123)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-19312
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human,
Non-human primate
宿主/亚型
Mouse
/ IgG3
分类
Monoclonal
类型
Antibody
克隆号
MEM-123
抗原
COS-7 cells.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 8
内含物
15mM sodium azide
保存条件
4°C, do not freeze
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody reacts with an extracellular epitope of all human classical MHC Class I molecules (major histocompatibility complex) in native cell-surface forms as well as with human HLA-G cDNA transfected cells. MHC Class I molecules (MHC Class Ia) are expressed on the surface of all human cell types. The antibody MEM-123 completely blocks binding of classical W6/32 to surface-expressed HLA-G, but does not cross-blocks the antibody MEM-G/9.
靶标信息
HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumor defense. Human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: H-2K; H-2K(d); H2-K; HLA class I histocompatibility antigen, A alpha chain; HLA class I histocompatibility antigen, B alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA-A; HLA-B; HLA-B 1502; HLA-C; HLA-Cw; Human leukocyte antigen A; Human leukocyte antigen B; Human leukocyte antigen C; leucocyte antigen A; MGC184092; MGC7052; MHC 1; MHC Class 1; MHC class I; MHC HLA-ABC; MHC I HLA; MHC1
基因别名: HLA-A; HLA-B; HLA-C; HLAA; HLAB; HLAC
Entrez Gene ID: (Human) 3105, (Human) 3106, (Human) 3107
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
