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Invitrogen
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MA1-20191 detects HP1 beta in human and mouse samples.
MA1-20191 has been successfully used in ELISA, immunohistochemistry (frozen) and Western blot procedures.
The MA1-20191 immunogen is a 71 amino acid fusion protein corresponding to the c-terminal region of M31 (human/mouse).
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。