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Invitrogen
Acetyl-alpha Tubulin (Lys40) Monoclonal Antibody (6-11B-1)
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产品信息
MA1-20250
应用
建议稀释比
已发表文章
产品规格
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
6-11B-1
抗原
Acetylated tubulin from the outer arm of Strongylocentrotus purpuratus (sea urchin).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
MA1-20250 detects tubulin (acetyl K40) in human, mouse, rat, bovine, algae, hamster, xenopus laevis, sea urchin, and porcine samples.
MA1-20250 has been successfully used in ELISA, ICC/IF, immunohistochemistry, dot blot, radioimmunoassay and Western blot procedures.
The MA1-20250 immunogen corresponds to acetylated tubulin from the outer arm of Strongylocentrotus purpuratus (sea urchin).
靶标信息
Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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