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Invitrogen
pro-Brain Natriuretic Peptide Monoclonal Antibody (11D1)
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pro-Brain Natriuretic Peptide Antibody (MA1-20584) in WB
Detection of human recombinant proBNP expressed mammalian cells in Western blotting by different monoclonal antibodies after Tricine-SDS gel electrophoresis. Antigen: recombinant proBNP expressed in mammalian cells, 0.15 ug; Lane 1: pro-Brain Natriuretic Peptide Monoclonal Antibody (5B6) (Product # MA1-20622); Lane 2: pro-Brain Natriuretic Peptide Monoclonal Antibody (15F11) (Product # MA1-20626); Lane 3: p... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-20584
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
11D1
抗原
Synthetic N-terminal pro brain natriuretic peptide (NT-proBNP), corresponding to amino acid residues a.a. 28-45. The peptides used for immunization were conjugated with carrier protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
5.2 mg/mL
规格
200 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA1-20584 detects proBNP in human samples.
靶标信息
In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BNP32; Brain natriuretic factor prohormone; Gamma-brain natriuretic peptide; Iso-ANP; Natriuretic peptides B; NTproBNP; preproBNP; pro-BNP
基因别名: NPPB
Entrez Gene ID: (Human) 4879
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