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Invitrogen
Human Papilloma Virus Type 16 E7 Monoclonal Antibody (SPM405)
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产品信息
MA1-21448
产品规格
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
SPM405
抗原
Recombinant full length protein (HPV type 16).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
保存条件
4°C
运输条件
Wet ice
产品详细信息
MA1-21448 detects Papillomavirus Type 16 E7 Protein in Virus samples.
MA1-21448 has been successfully used in FACS and Immunofluorescence procedures.
MA1-21448 immunogen corresponds to Recombinant full length protein (HPV type 16)..
靶标信息
The HPV E7 proteins are small (HPV16 E7 comprising 98 amino acids, 15kDa), zinc binding phosphoproteins which are localised in the nucleus. They are structurally and functionally similar to the E1A protein of subgenus C adenoviruses. The first 16 amino-terminal amino acids of HPV16 E7 contain a region homologous to a segment of the conserved region 1 (CR1) of the E1A protein of subgenus C adenoviruses. The next domain, up to amino acid 37, is homologous to the entire region 2 (CR2) of E1A. Genetic studies have established that these domains are required for cell transformation in vitro, suggesting similarities in the mechanism of transformation by these viruses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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