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Invitrogen
NME1 Monoclonal Antibody (37.6)
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产品信息
MA1-34943
产品规格
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
37.6
抗原
Purified human erythrocytes nucleoside diphosphate kinase A (nm23-H1)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C, do not freeze
运输条件
Wet ice
产品详细信息
MA1-34943 detects nm23 from human samples.
MA1-34943 has been successfully used in immunohistochemistry (paraffin & frozen tissue) applications.
The MA1-34943 immunogen is: Purified human erythrocytes nucleoside diphosphate kinase A (nm23-H1)
靶标信息
NME1 was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in the gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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