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Invitrogen
RANK Monoclonal Antibody (9A725), PE
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RANK Antibody (MA1-41015) in Flow
Flow cytometry analysis of RANK in K-562 cells. Samples were incubated with RANK monoclonal antibody (Product # MA1-41015) using a dilution of 1 µg/mL for 30 minutes at room temperature. An intracellular stain was performed with primary antibody (blue) and a matched isotype control (orange). Cells were fixed with 4% PFA and then permeabilized with 0.1% saponin.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA1-41015
产品规格
种属反应
Avian,
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
9A725
抗原
A fusion protein containing amino acid residues 326-616 of human RANK. Recognizes an epitope located between amino acid residues 330-427 of human RANK.
偶联物
PE
PE
PE
激发/发射光谱
565/576 nm
查看光谱
形式
Liquid
浓度
0.47 mg/mL
规格
47 µg
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
4°C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody recognizes an epitope located between amino acid residues 330-427 of human RaNK.
Suggested positive control: Raw.
靶标信息
RANK is a member of the tumor necrosis factor receptor (TNFR) family. The full length mouse RANK cDNA encodes a type I transmembrane protein with an extracellular and a cytoplasmic domain. The extracellular domain contains two potential N-linked glycosylation sites. RANK shares significant amino acid homology with other members of the TNFR family in its extracellular four cysteine-rich repeats. Human and murine RANK share 81% amino acid identity in their extracellular domains.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
How to use the Panel Builder
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生物信息学
蛋白别名: CD265; ODFR; Osteoclast differentiation factor receptor; receptor activator of NF-kappaB; Receptor activator of NF-KB; Tumor necrosis factor receptor superfamily member 11A
基因别名: Ly109; mRANK; ODFR; OFE; RANK; RGD1563614; TNFRSF11A; TRANCE-R
UniProt ID: (Mouse) O35305
Entrez Gene ID: (Mouse) 21934, (Rat) 498206
ossification
adaptive immune response
multicellular organism development
programmed cell death
osteoclast differentiation
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
response to cytokine
response to tumor necrosis factor
positive regulation of JUN kinase activity
lymph node development
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
circadian temperature homeostasis
mammary gland alveolus development
response to interleukin-1
positive regulation of fever generation by positive regulation of prostaglandin secretion
TNFSF11-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling
response to radiation
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