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Invitrogen
D4-GDI Monoclonal Antibody (10D774)
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FIGURE: 1 / 3
D4-GDI Antibody (MA1-41181) in WB
Western blot analysis of D4-GDI in Jurkat cells. Samples were incubated with D4-GDI monoclonal antibody (Product # MA1-41181) using a dilution of 2 µg/mL. Cells were treated with 2 µM staurosporine for different time periods. Detects both the full-length and cleaved forms of D4GDI while D4-GDI (cleavage specific) specifically detects only the cleaved form of the protein.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA1-41181
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Monoclonal
Type
Antibody
Clone
10D774
Immunogen
A synthetic peptide corresponding to human D4-GDI/RhoGDI2.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Amount
100 µg
Purification
Protein G
Storage buffer
PBS with 0.02% gelatin
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Suggested positive control: antigen standard for ARHGDIB (transient overexpression lysate), Daudi or Jurkat.
Target Information
Acts as a ventralizing factor during embryogenesis. Inhibits axin-mediated JNK activation by binding axin and disrupting axin homodimerization. This in turn antagonizes a Wnt/beta-catenin-independent dorsalization pathway activated by AXIN/JNK-signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: d4 gdi; GDI LYGDI; Ly-GDI; Rho GDI 2; Rho GDP-dissociation inhibitor 2; Rho-GDI beta
Gene Aliases: ARHGDIB; GDIA2; GDID4; RAP1GN1
Entrez Gene ID: (Human) 397
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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