Invitrogen

ITGA9/ITGB1 Monoclonal Antibody (Y9A2)

问题与答案

问题与答案

问题与答案

Additional Information:

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产品信息

MA1-80920

应用

建议稀释比

已发表文章

流式细胞分析 (Flow)

Assay-dependent

-

免疫沉淀 (IP)

Assay-dependent

-

产品规格

种属反应

Guinea pig, Human, Pig

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

Y9A2

抗原

alpha9 integrin transfected lambda cells.

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

200 µg

纯化类型

Protein A

保存液

PBS, pH 7.4

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

For FACS analysis, use 10 µL of the suggested working dilution to label 1x10^6 cells in 100 µL.

Mouse anti Human Integrin alpha 9 beta 1 antibody, clone Y9A2 recognizes the human alpha9 integrin, a approximately 140 kDa glycoprotein expressed as a heterodimer in association with the beta1 integrin.

靶标信息

Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CD29; Fibronectin receptor subunit beta; Glycoprotein IIa; GPIIA; Integrin alpha-9; Integrin alpha-RLC; integrin beta 1; Integrin beta-1; integrin beta-1 subunit; integrin beta-1 subunit (cytoplasmic domain); Integrin beta1; integrin VLA-4 beta subunit; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); unnamed protein product; very late activation protein, beta polypeptide; VLA-4 subunit beta

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基因别名: ALPHA-RLC; CD29; FNRB; GPIIA; ITGA4L; ITGA9; ITGB1; MDF2; MSK12; RLC; VLA-BETA; VLAB

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UniProt ID: (Human) Q13797, (Pig) Q9GLP0, (Human) P05556

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Entrez Gene ID: (Pig) 100626707, (Human) 3680, (Pig) 397019, (Human) 3688, (Guinea pig) 100716659, (Guinea pig) 100719502

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protein binding signaling receptor activity metal ion binding integrin binding involved in cell-matrix adhesion protein heterodimerization activity magnesium ion binding virus receptor activity fibronectin binding protease binding actin binding integrin binding calcium ion binding coreceptor activity protein kinase binding C-X3-C chemokine binding laminin binding macromolecular complex binding cadherin binding cell adhesion molecule binding collagen binding involved in cell-matrix adhesion protein tyrosine kinase binding integrin

cell adhesion cell-matrix adhesion integrin-mediated signaling pathway neutrophil chemotaxis negative regulation of vasoconstriction cell-cell adhesion regulation of collagen catabolic process positive regulation of cell migration receptor internalization cell adhesion mediated by integrin cellular response to low-density lipoprotein particle stimulus positive regulation of protein localization to plasma membrane G1/S transition of mitotic cell cycle establishment of mitotic spindle orientation angiogenesis in utero embryonic development cell migration involved in sprouting angiogenesis positive regulation of neuroblast proliferation phagocytosis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway neuroblast proliferation muscle organ development myoblast fusion cell proliferation germ cell migration visual learning positive regulation of fibroblast migration response to muscle activity cell migration formation of radial glial scaffolds central nervous system neuron differentiation CD40 signaling pathway cell projection organization lamellipodium assembly B cell differentiation extracellular matrix organization neuron projection development cell-substrate adhesion cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion negative regulation of Rho protein signal transduction wound healing, spreading of epidermal cells maintenance of blood-brain barrier positive regulation of apoptotic process stress fiber assembly positive regulation of GTPase activity sarcomere organization myoblast differentiation negative regulation of neuron differentiation positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis viral entry into host cell mesodermal cell differentiation myoblast fate specification axon extension dendrite morphogenesis regulation of developmental process modulation of synaptic transmission leukocyte tethering or rolling regulation of cell cycle positive regulation of protein kinase B signaling positive regulation of glutamate uptake involved in transmission of nerve impulse cardiac muscle cell differentiation cardiac muscle cell myoblast differentiation cardiac cell fate specification regulation of biological quality basement membrane organization positive regulation of wound healing regulation of spontaneous synaptic transmission reactive gliosis positive regulation of vascular endothelial growth factor signaling pathway regulation of synapse pruning negative regulation of anoikis