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Invitrogen
Cytokeratin 10 Monoclonal Antibody (LHP1)
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产品信息
MA1-81470
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human,
Sheep
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
LHP1
抗原
Cytoskeletal extract from epidermis of normal human skin.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
4°C or -20°C if preferred
运输条件
Wet ice
产品详细信息
This product requires protein digestion pre-treatment of paraffin sections using trypsin or pronase. A suggested positive control for immunohistochemical applications is human normal skin.
靶标信息
Cytokeratins (CK) are intermediate filaments of epithelial cells, both in keratinizing tissue (i.e., skin) and non-keratinizing cells (i.e. mesothelial cells). Although not a traditional marker for endothelial cells, cytokeratins have also been found in some microvascular endothelial cells. At least 20 different cytokeratins (CK) in the molecular range of 40-70 kDa and isoelectric points of 5-8. 5 can be identified using two dimensional gel electrophoresis. Biochemically, most members of the CK family fall into one of two classes, type I (acidic polypeptides) and type II (basic polypeptides). At least one member of the acidic family and one member of the basic family is expressed in all epithelial cells. Monoclonal antibodies to cytokeratin proteins can be useful markers for tumor identification and classification.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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