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Invitrogen
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MA1-90266 detects AP2 Transcription Factor from mouse samples.
MA1-90266 has been successfully used in immunohistochemistry (paraffin tissue), Western blot applications.
The MA1-90266 immunogen is: BALB/C mice were injected with a peptide from the C-terminus of AP-2 alpha.
TFAP2A is a sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. TFAP2A is the only AP-2 protein required for early morphogenesis of the lens vesicle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。