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Invitrogen
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MA1-91070 detects c-Jun from human samples.
MA1-91070 has been successfully used in immunohistochemistry (frozen tissue), immunohistochemistry (paraffin tissue) applications.
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。