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Invitrogen
RAD51 Monoclonal Antibody (51RAD01)
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产品信息
MA1-91517
应用
建议稀释比
已发表文章
产品规格
已发表种属
Algae,
Human,
Mouse,
Protozoa,
Yeast
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
51RAD01
抗原
BALB/C mice were injected with recombinant Rad51 protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
100 µg
保存条件
4°C, do not freeze
运输条件
Wet ice
产品详细信息
MA1-91517 detects Rad51 from mouse, rat samples.
MA1-91517 has been successfully used in immunofluorescence, immunohistochemistry (paraffin tissue), immunoprecipitation, Western blot applications.
The MA1-91517 immunogen is: BALB/C mice were injected with recombinant Rad51 protein.
靶标信息
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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