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Invitrogen
Endothelin Monoclonal Antibody (3B8C9)
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产品信息
MA3-020
产品规格
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
3B8C9
抗原
Synthetic peptide corresponding to residues C(15) H L D I I W(21) of endothelin.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
MA3-020 detects endothelin (ET)-1, ET-2 and ET-3. This antibody shows no cross-reactivity with the peptides ET(15-20) and ET(15-22).
MA3-020 has been successfully used in ELISA procedures. By ELISA this antibody is useful in solid-phase or competitive solution based procedures particularly in the study of enzymatic processing of ET, and in the identification of putative enzyme inhibitors. MA3-020 can detect approximately 0.5 pmol/ml ET-1 by direct ELISA.
The MA3-020 immunogen is a synthetic peptide corresponding to residues C(15) H L D I I W(21) of endothelin. This sequence is conserved between numerous species.
靶标信息
Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms- ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart, and liver.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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