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          • Primary Antibodies ›
          • MVP Antibodies

          Invitrogen

          MVP Monoclonal Antibody (1032)

          Advanced Verification
          1 Published Figure
          4 References
          View all (27) MVP antibodies

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          Cite MVP Monoclonal Antibody (1032)

          Additional Information:
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          • Antibody Testing Data (4)
          • Published Figures (1)
          • Advanced Verification (2)
          MVP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          MVP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          MVP Antibody (MA5-13871) in IHC (P)

          Formalin-fixed, paraffin-embedded human breast carcinoma stained with LRP/MVP antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          View Product

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          MVP Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MVP Antibody in Western Blot (WB)
          MVP Antibody in Western Blot (WB)
          MVP Antibody in Western Blot (WB)
          MVP Antibody in Western Blot (WB)
          MVP Antibody
          MVP Antibody

          Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

          MVP Monoclonal Antibody (1032)

          Product Details

          MA5-13871

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1-2 µg/mL
          View 3 publications 3 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:100
          -

          Flow Cytometry (Flow)

          Assay-dependent
          -

          Immunoprecipitation (IP)

          2 µg/mL
          -

          Gel Shift (EMSA)

          1 mg/mL
          -
          Product Specifications

          Species Reactivity

          Human, Rat

          Published species

          Human

          Host/Isotype

          Mouse / IgG1, kappa

          Class

          Monoclonal

          Type

          Antibody

          Clone

          1032

          Immunogen

          Proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          100 µg

          Purification

          Protein A/G

          Storage buffer

          PBS, pH 7.4, with 0.05% BSA

          Contains

          0.05% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_10989340

          Product Specific Information

          MA5-13871 targets Major Vault Protein in FACS, GS, IHC (P), IP, and WB applications and shows reactivity with Human and Rat samples.

          The MA5-13871 immunogen is proteins precipitated with AER317 from the phosphocellulose column flow through of extract of human breast cancer MCF-7 cells.

          Target Information

          This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Lung resistance-related protein; Major vault protein; MVP; MVP1; Testicular Secretory Protein Li 30; VAULT1; vRNP

          View more View less

          Gene Aliases: LRP; MVP

          View more View less

          UniProt ID: (Rat) Q62667

          View more View less

          Entrez Gene ID: (Rat) 64681

          View more View less

          Function(s)
          protein binding protein kinase binding protein phosphatase binding scaffold/adaptor protein
          Process(es)
          cell proliferation negative regulation of signaling negative regulation of protein autophosphorylation ERBB signaling pathway negative regulation of protein tyrosine kinase activity protein activation cascade
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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