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MA5-14057 targets HER-2 in IHC (P), IP, ICC/IF, FACS and WB applications and shows reactivity with Human samples.
The MA5-14057 immunogen is cytoplasmic domain of recombinant human c-erbB-2/HER-2 oncoprotein (e2-4001) and a synthetic peptide from the C-terminus of human c-erbB-2 protein (3B5).
ErbB2 (HER2) is a receptor tyrosine kinase that is overexpressed in some breast tumors. Herceptin, used in treatment of metastatic Her2-positive cancer, is monoclonal antibody targeting this kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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