Invitrogen

Lamin A (Cleaved Asp230) Monoclonal Antibody (C.69.9)

Name: Lamin A (Cleaved Asp230) Monoclonal Antibody (C.69.9)
Brand: Invitrogen
SKU: MA5-15211
Availability: InStock

查看其他2个Lamin A (Cleaved Asp230)抗体

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

说明书

Certificates

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Lamin A (Cleaved Asp230) Antibody in Immunocytochemistry (ICC/IF)

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Lamin A (Cleaved Asp230) Antibody (MA5-15211) in ICC/IF

Immunofluorescent analysis of Cleaved Lamin A in HeLa cells using a Cleaved Lamin A monoclonal antibody (Product # MA5-15211).

Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.

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Immunogen image

Immunogen Image Lamin A (Cleaved Asp230) Monoclonal Antibody (C.69.9)

产品信息

MA5-15211

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000

免疫细胞化学 (ICC/IF)

1:100

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

C.69.9

抗原

Synthetic peptide corresponding to amino-terminal residues surrounding Asp230 of human lamin A

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 µg/mL

0.1 µg

纯化类型

Affinity chromatography

保存液

0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol

内含物

<0.02% sodium azide

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

AB_10985208

产品详细信息

It is not recommended to aliquot this antibody.

This antibody is not cross-reactive with full length lamin A or C.

靶标信息

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

仅用于科研。不用于诊断过程。未经明确授权不得转售。