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Invitrogen
GATA4 Monoclonal Antibody (6H10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-15532
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
6H10
抗原
Purified recombinant fragment of human GATA4 expressed in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-15532 targets GATA4 in indirect ELISA, WB and ChIP applications and shows reactivity with Human and mouse samples.
The MA5-15532 immunogen is purified recombinant fragment of human GATA4 expressed in E. Coli.
MA5-15532 detects GATA4 which has a predicted molecular weight of approximately 46kDa.
靶标信息
GATA4 is a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function. Mutations in the gene encoding GATA4 have been associated with cardiac septal defects.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DNA-binding protein GATA-GT2; GAT4; GATA-binding factor 4; GATA-binding protein 4; MGC126629; Transcription factor GATA-4
基因别名: Gata-4; Gata4
UniProt ID: (Mouse) Q08369, (Rat) P46152
Entrez Gene ID: (Mouse) 14463, (Rat) 54254
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II transcription factor binding
enhancer sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
transcription coactivator activity
protein binding
transcription factor binding
zinc ion binding
protein kinase binding
activating transcription factor binding
sequence-specific DNA binding
transcription regulatory region DNA binding
metal ion binding
NFAT protein binding
co-SMAD binding
DNA-binding transcription factor
in utero embryonic development
gastrulation with mouth forming second
endoderm formation
heart looping
heart morphogenesis
outflow tract morphogenesis
atrioventricular valve morphogenesis
atrioventricular valve formation
mitral valve formation
tricuspid valve formation
endocardial cushion development
cardiac right ventricle morphogenesis
ventricular cardiac muscle tissue development
cardiac septum development
ventricular septum development
atrial septum primum morphogenesis
atrial septum secundum morphogenesis
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell-cell signaling
spermatogenesis
heart development
male gonad development
response to mechanical stimulus
regulation of gene expression
negative regulation of autophagy
positive regulation of vascular endothelial growth factor production
cardiac muscle hypertrophy in response to stress
signal transduction involved in regulation of gene expression
BMP signaling pathway
positive regulation of BMP signaling pathway
response to retinoic acid
embryonic heart tube development
embryonic heart tube anterior/posterior pattern specification
tube morphogenesis
skeletal muscle cell differentiation
atrioventricular canal development
response to drug
response to estrogen
positive regulation of angiogenesis
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
embryonic digestive tract morphogenesis
embryonic morphogenesis
embryonic foregut morphogenesis
cardiac muscle tissue development
cardiac muscle cell differentiation
Sertoli cell differentiation
regulation of cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
transdifferentiation
SMAD protein signal transduction
atrial septum morphogenesis
lung morphogenesis
lung lobe formation
diaphragm morphogenesis
intestinal epithelial cell differentiation
vasculogenesis involved in coronary vascular morphogenesis
cell growth involved in cardiac muscle cell development
cellular response to gonadotropin stimulus
cellular response to follicle-stimulating hormone stimulus
epithelial cell fate commitment
seminiferous tubule development
regulation of cardiac muscle cell contraction
response to vitamin A
positive regulation of cardioblast differentiation
cellular response to glucose stimulus
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
