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Invitrogen
VEGF Receptor 1 Monoclonal Antibody (3D10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-15550
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3D10
抗原
Purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-15550 targets FLT1 in indirect ELISA, WB applications and shows reactivity with Human samples.
The MA5-15550 immunogen is purified recombinant extracellular fragment of human FLT1 fused with hIgGFc tag expressed in HEK293 cells.
MA5-15550 detects FLT1 which has a predicted molecular weight of approximately 100kDa.
靶标信息
FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: i21; soluble VEGFR 1; sVEGFR 1; VEGF R1
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