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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-15596 targets Pirh2 in indirect ELISA, FACS, IF, IHC, and WB applications and shows reactivity with Human and Rat samples.
The MA5-15596 immunogen is purified recombinant fragment of human Pirh2 expressed in E. Coli.
MA5-15596 detects Pirh2 which has a predicted molecular weight of approximately 30kDa; 60kDa (homodimer).
The protein encoded by this gene has ubiquitin-protein ligase activity. This protein binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. This gene is oncogenic because loss of p53 function contributes directly to malignant tumor development. Transcription of this gene is regulated by p53. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZp586C1620; h PRO1996; PIRH2E; PIRH2F; RING finger and CHY zinc finger domain-containing protein 1
Entrez Gene ID: (Rat) 289508