Search
Invitrogen
IKK alpha Monoclonal Antibody (3G12H9)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-15696
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3G12H9
抗原
Purified recombinant fragment of human CHUK expressed in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
Conc. Not Determined
保存液
ascites
内含物
0.03% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
MA5-15696 targets CHUK in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples.
The MA5-15696 immunogen is purified recombinant fragment of human CHUK expressed in E. Coli.
MA5-15696 detects CHUK which has a predicted molecular weight of approximately 85kDa.
靶标信息
CHUK (IKK alpha) is a serine/threonine kinase involved in signal transduction and cellular communication. It belongs to the cytokine activated protein complex that is an inhibitor of the NF-kappa B complex. IKK alpha along with IKK beta and a regulatory protein NEMO (IKK gamma) phosphorylates IkB proteins which targets the later for ubiquitin mediated degradation. It is involved with several cellular processes with extensive studies on its role in inflammation and cell survival.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: EC 2.7.11.10; FLJ40509; I kappa B kinase 1; I-kappa-B kinase 1; I-kappa-B kinase 2; I-kappa-B kinase alpha; ikappaB kinase; IkappaB kinase alpha; IKBKB; IKK alpha; IKK-A; IKK-B; IKK-beta; IKK2; IKKB; inhibitor of nuclear factor kappa-B kinase subunit alpha; kinase beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase alpha
基因别名: AI256658; Chuk1; Fbx24; Fbxo24; IKBKA; IKK1; Ikka; NFKBIKA
Entrez Gene ID: (Mouse) 12675
nucleotide binding
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding
non-receptor serine/threonine protein kinase
protein modifying enzyme
morphogenesis of an epithelial sheet
protein phosphorylation
I-kappaB phosphorylation
Rho protein signal transduction
lactation
response to organic substance
phosphorylation
signal transduction by protein phosphorylation
osteoclast differentiation
response to lipopolysaccharide
mammary gland epithelial cell proliferation
response to muscle stretch
odontogenesis of dentin-containing tooth
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
striated muscle cell differentiation
mammary gland alveolus development
cellular response to tumor necrosis factor
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
