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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-16308-D800 detects bet-Tubulin from various species. MA5-16308-D800 has been successfully used for fluorescent detection of beta-Tubulin in Western Blotting.
DyLight 800 4X PEG has an excitation/emission of 783/797 nm.
Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Beta-III tubulin is primarily expressed in neurons and may be involved in neurogenesis, axon guidance and maintenance. Mutations in the beta tubulin gene are the cause of congenital fibrosis of the extraocular muscles type 3. Beta-III tubulin was also detected in Sertoli cells of the testis and transiently in non-neuronal embryonic tissues. Glutamate residues at the C-terminus of beta III tubulin can be glutamylated. The precise function of such modifications is unclear. Tubulin is phosphorylated on Ser-172 by CDK1 during cell cycle progression. Ser-172 phosphorylation inhibits tubulin incorporation into microtubules.Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55 kDa subunits: alpha and Beta. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton. Because beta-tubulin is ubiquitously expressed in all eukaryotic cells, it is frequently used as a loading control for assays involving protein detection, such as Western blotting.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: beta tubulin; beta tubulin 1; beta-4 tubulin; beta-tubulin; beta-tubulin 1; beta-tubulin 2; beta-tubulin 3; beta-tubulin 4; beta-tubulin 5; beta-tubulin 6; beta-tubulin 7; beta-tubulin 8; beta-tubulin 9; beta-tubulin T beta15 (aa 1-445); betaIII-tubulin; dJ40E16.7; M40 antibody; Neuron-specific class III beta-tubulin; T beta-15; TUB; TUB1; TUB2; TUB3; TUB4; TUB5; TUB6; TUB7; TUB8; TUB9; TUBB; tubb2a {ECO:0000250|UniProtKB:Q7TMM9}; Tubulin 5 beta; tubulin beta; Tubulin beta 8 class VIII; Tubulin beta chain; Tubulin beta class IIa; Tubulin beta class V; Tubulin beta-1 chain; Tubulin beta-2A chain; Tubulin beta-2B chain; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-4A chain; Tubulin beta-5 chain; Tubulin beta-6 chain; Tubulin beta-8 chain; Tubulin beta-III; tubulin, beta 1 class VI; tubulin, beta 2; tubulin, beta 4; tubulin, beta 4 class IVa; tubulin, beta polypeptide
基因别名: 2310057H16Rik; 2410129E14Rik; 2810484G07Rik; 3200002H15Rik; AA408537; AI325297; AI596182; B130022C14Rik; BB220206; brdp; M(beta)1; M(beta)2; M(beta)3; M(beta)4; M(beta)5; M(beta)6; OK/SW-cl.56; RGD1305887; RGD1309427; TUBB; TUBB1; TUBB2; TUBB2A; TUBB2B; TUBB3; TUBB4; TUBB4A; TUBB5; TUBB6; TUBB8