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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-17063 targets CYP1A1 in IHC, indirect ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17063 immunogen is purified recombinant fragment of human CYP1A1 expressed in E. Coli.
MA5-17063 detects CYP1A1 which has a predicted molecular weight of approximately 58kDa.
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CYP; CYPIA1; Cytochrome P450 1A1; Cytochrome P450 form 6; Cytochrome P450-C; Cytochrome P450-P1; Hydroperoxy icosatetraenoate dehydratase; P450; P450 form 6; P450-P1
基因别名: CYP1A1
Entrez Gene ID: (Human) 1543