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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
MA5-17098 targets IL34 in indirect ELISA, FACS, ICC, IF, and WB applications and shows reactivity with Human samples.
The MA5-17098 immunogen is purified recombinant fragment of human IL34 expressed in E. Coli.
MA5-17098 detects IL34 which has a predicted molecular weight of approximately 27.5kDa.
IL-34 is secreted as a dimeric protein and currently belongs to no known cytokine family. It signals via the M-CSF Receptor, also known as CSF-1R and CD115, which is shared with M-CSF. IL-34 has no amino acid sequence homology to M-CSF, but they exhibit similarities in secondary structure and share overlapping functions. IL-34 has been shown to promote myeloid survival, proliferation, and differentiation, and to play a role in osteoclast formation. IL-34 expression has been detected in various tissues and is most abundant in the spleen.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: IL-34; ILN; Interleukin; Interleukin-34; Interleukin34
基因别名: C16orf77; IL34
Entrez Gene ID: (Human) 146433