Search
Invitrogen
IL1RA Monoclonal Antibody (02)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
图: 1 / 6
IL1RA Antibody (MA5-29352) in ICC/IF
Immunofluorescence staining of Human IL1Ra in Hela cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with IL1RA Monoclonal Antibody (2) (Product # MA5-29352, 1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (green). Positive staining was localized to cytoplasm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-29352
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
02
抗原
Recombinant Human IL-1RA protein (Arg26-Glu177)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human IL-1RA.
靶标信息
The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: CD121A; D2S1473; IL 1 receptor antagonist; il-1 receptor; il-1r; IL-1R-alpha; IL-1RN; IL1 inhibitor; il1 receptor; IL1 receptor antagonist; IL1-RA; IL1R; IL1RN (IL1F3); interleukin-1 receptor; Interleukin-1 receptor antagonist protein; IRAP; MGC10430; P80
基因别名: F630041P17Rik; IL-1ra; Il1rn
UniProt ID: (Mouse) P25085, (Rat) P25086
Entrez Gene ID: (Mouse) 16181, (Rat) 60582
fever generation
negative regulation of cytokine-mediated signaling pathway
lipid metabolic process
acute-phase response
memory
negative regulation of glutamate secretion
cytokine-mediated signaling pathway
sensory perception of pain
insulin secretion
negative regulation of cell migration
negative regulation of heterotypic cell-cell adhesion
negative regulation of apoptotic process
positive regulation of JUN kinase activity
negative regulation of membrane potential
response to glucocorticoid
extracellular negative regulation of signal transduction
negative regulation of receptor activity
negative regulation of interleukin-1-mediated signaling pathway
chronic inflammatory response to antigenic stimulus
female pregnancy
negative regulation of signal transduction
response to organonitrogen compound
response to organic cyclic compound
response to activity
carboxylic acid metabolic process
response to lipopolysaccharide
response to drug
response to starvation
response to interleukin-1
response to interleukin-4
cellular response to norepinephrine stimulus
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
