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Invitrogen
5T4 Recombinant Rabbit Monoclonal Antibody (SU34-05)
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Product Details
MA5-32120
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
SU34-05
Immunogen
Synthetic peptide within Human 5T4 aa 381-420.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 5T4 oncofetal antigen; 5T4 oncofetal trophoblast glycoprotein; 5T4 oncotrophoblast glycoprotein; 5T4-AG; M6P1; Trophoblast glycoprotein; unnamed protein product; WAIF1; Wnt-activated inhibitory factor 1
Gene Aliases: 5T4; 5T4AG; AW495680; M6P1; TPBG; WAIF1
UniProt ID: (Human) Q13641, (Mouse) Q9Z0L0, (Rat) Q5PQV5
Entrez Gene ID: (Human) 7162, (Mouse) 21983, (Rat) 83684
positive regulation of synapse assembly
cell adhesion
negative regulation of cell proliferation
olfactory learning
positive regulation of chemotaxis
positive regulation of protein kinase B signaling
synaptic transmission, GABAergic
cell chemotaxis
positive regulation of ERK1 and ERK2 cascade
protein localization to plasma membrane
negative regulation of canonical Wnt signaling pathway
mesenchymal cell migration
dendrite arborization
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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