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Invitrogen
Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98)
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图: 1 / 13
Aquaporin 1 Antibody (MA5-32593) in ICC/IF
Immunofluorescence analysis of AQP1 was performed using 70% confluent log phase HeLa cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Aquaporin 1 Recombinant Rabbit Monoclonal Antibody (JM10-98) (Product # MA5-32593) at 5 µg/mL in 0.1% BSA, incubated a... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-32593
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JM10-98
抗原
Synthetic peptide within Human AQP1 aa 245-269.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
Aquaporin 1 is a 28kD integral membrane protein which was originally identified in red blood cells and renal proximal tubules. AQP1 is also expressed by the choroid plexus and various other tissues. It forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: AQP 1; AQP CHIP; AQP-1; Aquaporin 1 (aquaporin channel forming integral protein 28 (CHIP)); Aquaporin CHIP; Aquaporin-1; Aquaporin-CHIP; Aquaporin1; Channel-like integral membrane protein of 28 kDa; CHIP 28; Colton blood group; Delayed early response protein 2; DER2; growth factor-induced delayed early response protein; MGC26324; Urine water channel; water channel protein for red blood cells and kidney proximal tubule
基因别名: AQP1; CHIP28
UniProt ID: (Mouse) Q02013, (Rat) P29975
Entrez Gene ID: (Mouse) 11826, (Rat) 25240
transporter activity
intracellular cGMP activated cation channel activity
potassium channel activity
water transmembrane transporter activity
ammonium transmembrane transporter activity
potassium ion transmembrane transporter activity
glycerol transmembrane transporter activity
water channel activity
glycerol channel activity
transmembrane transporter activity
nitric oxide transmembrane transporter activity
carbon dioxide transmembrane transporter activity
ephrin receptor binding
protein binding
transporter
glomerular filtration
renal water transport
cGMP biosynthetic process
transport
potassium ion transport
water transport
cell volume homeostasis
cellular water homeostasis
positive regulation of lamellipodium assembly
positive regulation of epithelial cell migration
carbon dioxide transport
organic cation transport
ammonium transport
glycerol transport
sensory perception of pain
cellular homeostasis
water homeostasis
nitric oxide transport
positive regulation of cell migration
establishment or maintenance of actin cytoskeleton polarity
secretion by cell
secretory granule organization
cellular response to stress
carbohydrate transmembrane transport
cellular response to UV
transepithelial water transport
carbon dioxide transmembrane transport
wound healing
response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
lipid digestion
positive regulation of angiogenesis
positive regulation of saliva secretion
positive regulation of fibroblast proliferation
camera-type eye morphogenesis
corticotropin secretion
transmembrane transport
renal water absorption
cellular response to hydrogen peroxide
cellular response to inorganic substance
cellular response to mechanical stimulus
cellular response to copper ion
cellular response to mercury ion
cellular response to retinoic acid
cellular response to cAMP
cellular response to hypoxia
cellular response to salt stress
cellular hyperosmotic response
cellular response to dexamethasone stimulus
cellular response to nitric oxide
potassium ion transmembrane transport
ammonium transmembrane transport
maintenance of symbiont-containing vacuole by host
cation transmembrane transport
hyperosmotic response
response to hormone
lateral ventricle development
pancreatic juice secretion
cerebrospinal fluid secretion
odontogenesis
hyperosmotic salinity response
response to estrogen
multicellular organismal water homeostasis
metanephric descending thin limb development
metanephric proximal straight tubule development
metanephric proximal convoluted tubule segment 2 development
metanephric glomerulus vasculature development
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