Invitrogen

Nogo-B Recombinant Rabbit Monoclonal Antibody (JM02-34)

Name: Nogo-B Recombinant Rabbit Monoclonal Antibody (JM02-34)
Brand: Invitrogen
SKU: MA5-32763

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说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

Nogo-B Antibody in Immunocytochemistry (ICC/IF)

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Nogo-B Antibody (MA5-32763) in ICC/IF

Immunocytochemical analysis of Nogo-B in SH-SY5Y cells using a Nogo-B Monoclonal antibody (Product # MA5-32763) as seen in green. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.

Nogo-B Antibody in Immunohistochemistry (Paraffin) (IHC (P))

Nogo-B Antibody in Flow Cytometry (Flow)

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Immunogen image

Immunogen Image Nogo-B Recombinant Rabbit Monoclonal Antibody (JM02-34)

产品信息

MA5-32763

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:1,000-1:2,000

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免疫组化（石蜡） (IHC (P))

1:200-1:1,000

免疫细胞化学 (ICC/IF)

1:50-1:200

流式细胞分析 (Flow)

1:1,000

免疫沉淀 (IP)

1:10-1:50

产品规格

种属反应

Human, Mouse

宿主/亚型

Rabbit / IgG

Expression System

HEK293 cells

分类

Recombinant Monoclonal

类型

Antibody

克隆号

JM02-34

抗原

Synthetic peptide within Human Nogo aa 111-160.

3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

100 µg

纯化类型

Protein A

保存液

TBS, pH 7.4, with 40% Glycerol, 0.05% BSA

内含物

0.05% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2810040

产品详细信息

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

靶标信息

Nogo-B is a member of the reticulon-4 (RTN4) family of proteins, primarily localized to the endoplasmic reticulum and expressed in many tissues, especially vascular endothelial and smooth muscle cells. It plays a key role in regulating vascular remodeling, cell migration, and tissue repair by influencing cytoskeletal organization and signaling pathways. Unlike Nogo-A, which is known for inhibiting nerve regeneration, Nogo-B is more involved in maintaining vascular homeostasis and modulating inflammatory responses.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

生物信息学

蛋白别名: ASY; Foocen; Human NogoA; My043 protein; neurite growth inhibitor 220; Neurite outgrowth inhibitor; Neuroendocrine-specific protein; Neuroendocrine-specific protein C homolog; Nogo protein; NOGO-A; RTN4-A; NOGO-B; RTN4-B1; NOGO-C; RTN4-C; NSP; reticulon; reticulon 5; Reticulon-4; Reticulon-5; RTN-x; RTN4-Aa; RTN4-Ab; RTN4-B2; RTN4-D; RTN4-E; RTN4-F; RTN4-G; RTN4a; RTN4b; RTN4c; unnamed protein product

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基因别名: 1110020G17Rik; AA407876; AA409940; AA960376; ASY; C130026I10Rik; KIAA0886; mKIAA0886; mKIAA4153; My043; Nbla00271; Nbla10545; NgA; NI220/250; NOGO; Nogo-A; Nogo-B; Nogo-C; NSP; NSP-CL; RTN-X; RTN4; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C; SP1507

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UniProt ID: (Human) Q9NQC3, (Mouse) Q99P72

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Entrez Gene ID: (Human) 57142, (Mouse) 68585

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功能

RNA binding protein binding ubiquitin protein ligase binding protein homodimerization activity cadherin binding metal ion binding protein complex binding poly(A) RNA binding

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