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Invitrogen
TXNIP Recombinant Rabbit Monoclonal Antibody (JM60-35)
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图: 1 / 17
TXNIP Antibody (MA5-32771) in ICC/IF
Immunofluorescence analysis of TXNIP was performed using 70-80% confluent log phase HaCaT cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with TXNIP Recombinant Rabbit Monoclonal Antibody (JM60-35) (Product # MA5-32771, 1:100) in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy chain), Superclonal™ Recombinant Secondary Antibody, Alex... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-32771
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
JM60-35
抗原
Synthetic peptide within Human TXNIP aa 50-99.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: hyperlipidemia 1; thioredoxin binding protein-2; Thioredoxin-binding protein 2; Thioredoxin-interacting protein; upregulated by 1,25-dihydroxyvitamin D-3; Vitamin D3 up-regulated protein 1
基因别名: 1200008J08Rik; AA682105; Hyplip1; Tbp-2; THIF; TXNIP; VDUP1
UniProt ID: (Rat) Q5M7W1, (Mouse) Q8BG60
Entrez Gene ID: (Rat) 117514, (Mouse) 56338
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
protein import into nucleus
response to oxidative stress
response to mechanical stimulus
response to glucose
keratinocyte differentiation
response to estradiol
response to progesterone
regulation of cell proliferation
response to drug
response to hydrogen peroxide
positive regulation of apoptotic process
negative regulation of catalytic activity
platelet-derived growth factor receptor signaling pathway
response to calcium ion
negative regulation of cell division
cellular response to tumor cell
regulation of transcription, DNA-templated
cell cycle
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
