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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DLDBP; E3BP; Glucose-sensitive factor; GSF; IDX-1; Insulin promoter factor 1; Insulin upstream factor 1; IPF-1; Islet/duodenum homeobox-1; IUF-1; Pancreas/duodenum homeobox protein 1; PDHX; PDX-1; Somatostatin-transactivating factor 1; STF-1
基因别名: IPF1; PDX1; STF1
Entrez Gene ID: (Human) 3651