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Invitrogen
MYH7 Monoclonal Antibody (NOQ7.5.4D)
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MYH7 Antibody (MA5-32986) in IHC (P)
Immunohistochemistry (Paraffin) analysis of MYH7 in paraffin-embedded section of rat skeletal muscle tissue using MYH7 Monoclonal Antibody (NOQ7.5.4D) (Product # MA5-32986). Heat mediated antigen retrieval was performed in EDTA buffer (pH 8.0, epitope retrieval solution). The tissue section was blocked with 10% goat serum. The tissue section was then incubated with the primary antibody at a 2 µg/mL dilution... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-32986
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
NOQ7.5.4D
抗原
Human skeletal muscle myosin purified from myofibrils.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
100 µg/mL
规格
100 µg
保存液
ascites/1.2% sodium acetate with 2mg BSA
内含物
0.01mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 1 mL of PBS buffer to yield a concentration of 100 µg/mL.
Positive Control - WB: rat heart tissue.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: beta myosin heavy chain; cardiac myosin heavy chain beta isoform; MYH-beta/slow; MyHC-beta; MyHC-slow; Myosin heavy chain 7; myosin heavy chain polypeptide 7 cardiac muscle fetal; Myosin heavy chain slow isoform; Myosin heavy chain, cardiac muscle beta isoform; myosin heavy chain, cardiac muscle, fetal; myosin heavy chain, polypeptide 7; myosin, heavy polypeptide 7, cardiac muscle, beta; Myosin-7
基因别名: B-MHC; beta-MHC; Myh7; Myhc-b; MyHC-I; Myhcb
UniProt ID: (Mouse) Q91Z83, (Rat) P02564
Entrez Gene ID: (Mouse) 140781, (Rat) 29557
regulation of the force of heart contraction
regulation of heart rate
skeletal muscle contraction
muscle contraction
striated muscle contraction
adult heart development
metabolic process
regulation of the force of skeletal muscle contraction
transition between fast and slow fiber
muscle filament sliding
regulation of slow-twitch skeletal muscle fiber contraction
ATP metabolic process
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
response to reactive oxygen species
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
