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Invitrogen
ALDH2 Recombinant Rabbit Monoclonal Antibody (1J9I8)
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FIGURE: 1 / 3
ALDH2 Antibody (MA5-35122) in WB
Western blot was performed using Anti-ALDH2 Recombinant Rabbit Monoclonal Antibody (ARC0623) (Product # MA5-35122) and a 56 kDa band corresponding to acetaldehyde dehydrogenase 2; ALDH2 was observed across the panel tested except for PANC-1, MCF7 and mouse brain which are reported to be low expressors of ALDH2. Whole cell extracts (30 µg lysate) of THP-1 (Lane 1), Hep G2 (Lane 2), A549 (Lane 3), PANC-1 (Lane 4), MCF7 (Lane 5), Mouse Liver (Lane 6), Mouse Lung (Lane 7), Mouse Brain (Lane 8), Rat Liver (Lane 10) were electrophoresed using Nu... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-35122
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1J9I8
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: HRGRLLNRLA DLIERDRTYL AALETLDNGK PYVISYLVDL DMVLKCLRYY AGWADKYHGK TIPIDGDFFS YTRHEPVGVC GQIIPWNFPL LMQAWKLGPA L
Target Information
ALDH2 belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Asians have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Asians than among Caucasians could be related to the absence of the mitochondrial isozyme.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AHD-M1; aldehyde dehydrogenase 2, mitochondrial; Aldehyde dehydrogenase, mitochondrial; ALDH class 2; ALDH-E2; ALDH1; ALDHI; EC 1.2.1.3; MGC1806; mitochondrial aldehyde dehydrogenase
Gene Aliases: Ahd-1; Ahd-5; AHD-M1; Ahd1; Ahd5; ALDH-E2; ALDH2; ALDHI; ALDM
UniProt ID: (Rat) P11884, (Mouse) P47738
Entrez Gene ID: (Rat) 29539, (Mouse) 11669
liver development
ethanol catabolic process
response to estradiol
response to lipopolysaccharide
response to progesterone
cellular response to hormone stimulus
response to testosterone
response to nicotine
negative regulation of apoptotic process
response to hyperoxia
oxidation-reduction process
cellular response to fatty acid
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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