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Invitrogen
UBC9 Recombinant Rabbit Monoclonal Antibody (6Z9V6)
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图: 1 / 5
UBC9 Antibody (MA5-35505) in IHC (P)
Immunohistochemistry analysis of UBC9 in paraffin-embedded human colon carcinoma. Samples were incubated with UBC9 Monoclonal antibody (Product # MA5-35505) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-35505
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
6Z9V6
抗原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human UBE2I (P63279)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.55 mg/mL
规格
55 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MSGIALSRLA QERKAWRKDH PFGFVAVPTK NPDGTMNLMN WECAIPGKKG TPWEGGLFKL RMLFKDDYPS SPPKCKFEPP LFHPNVYPSG TVCLSILEED
靶标信息
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: mUBC9; OTTHUMP00000198131; p18; RING-type E3 SUMO transferase UBC9; SUMO-conjugating enzyme UBC9; SUMO-protein ligase; Ubiquitin carrier protein 9; Ubiquitin carrier protein I; Ubiquitin conjugating enzyme E2I (homologous to yeast UBC9); Ubiquitin-conjugating enzyme E2 I; ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast); Ubiquitin-conjugating enzyme UbcE2A; Ubiquitin-protein ligase I
基因别名: 5830467E05Rik; F830028O17Rik; UBC9; UbcE2A; Ubce2i; UBCE9; UBE2I
UniProt ID: (Rat) P63281, (Mouse) P63280
Entrez Gene ID: (Rat) 25573, (Mouse) 22196
ubiquitin-protein transferase activity
protein binding
ATP binding
protein C-terminus binding
transcription factor binding
ligase activity
SUMO transferase activity
enzyme binding
ubiquitin protein ligase binding
HLH domain binding
bHLH transcription factor binding
poly(A) RNA binding
ubiquitin protein ligase activity
SUMO conjugating enzyme activity
RING-like zinc finger domain binding
nucleotide binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
negative regulation of transcription from RNA polymerase II promoter
ubiquitin-dependent protein catabolic process
chromosome segregation
mitotic nuclear division
regulation of receptor activity
protein ubiquitination
protein sumoylation
positive regulation of intracellular steroid hormone receptor signaling pathway
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
negative regulation of transcription, DNA-templated
positive regulation of sequence-specific DNA binding transcription factor activity
cell division
positive regulation of SUMO transferase activity
cellular protein modification process
cell cycle
multicellular organism development
viral process
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