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Invitrogen
FOXP1 Recombinant Rabbit Monoclonal Antibody (2Q1R5)
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FOXP1 Antibody (MA5-35803) in WB
Western blot analysis of FOXP1 in various lysates. Samples were incubated with FOXP1 Monoclonal antibody (Product # MA5-35803) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 180s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-35803
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
2Q1R5
抗原
Recombinant Protein corresponding to a sequence within amino acids 550-650 of human FOXP1 (Q9H334)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: SGNPSLIKNM QSSHAYCTPL NAALQASMAE NSIPLYTTAS MGNPTLGNLA SAIREELNGA MEHTNSNESD SSPGRSPMQA VHPVHVKEEP LDPEEAEGPL S
靶标信息
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FLJ23741; Fork head related protein like B; Forkhead box protein P1; Forkhead box protein P1 (FOXP1); Forkhead-related transcription factor 1; Glutamine rich factor 1; Mac-1-regulated forkhead; MFH; MGC12942; MGC88572; MGC99551
基因别名: 3110052D19Rik; 4932443N09Rik; AI461938; AW494214; FOXP1; HSPC215
UniProt ID: (Rat) Q498D1, (Mouse) P58462
Entrez Gene ID: (Rat) 297480, (Mouse) 108655
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
DNA binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
protein homodimerization activity
metal ion binding
protein heterodimerization activity
androgen receptor binding
protein binding
sequence-specific DNA binding
negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
positive regulation of mesenchymal cell proliferation
pre-B cell differentiation
positive regulation of immunoglobulin production
negative regulation of B cell apoptotic process
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
heart development
skeletal muscle tissue development
motor neuron axon guidance
positive regulation of endothelial cell migration
ventral spinal cord development
osteoclast differentiation
lung development
response to lipopolysaccharide
regulation of tumor necrosis factor production
immunoglobulin V(D)J recombination
chemokine (C-C motif) ligand 2 secretion
osteoclast development
macrophage activation
monocyte activation
endothelial cell activation
sarcomere organization
regulation of monocyte differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of smooth muscle cell proliferation
smooth muscle tissue development
positive regulation of epithelial cell proliferation
regulation of interleukin-1 beta secretion
regulation of inflammatory response
cardiac muscle cell differentiation
regulation of cardiac muscle cell proliferation
negative regulation of androgen receptor signaling pathway
lung secretory cell differentiation
T follicular helper cell differentiation
cardiovascular system development
interleukin-21 secretion
regulation of defense response to bacterium
regulation of lung goblet cell differentiation
negative regulation of lung goblet cell differentiation
regulation of macrophage colony-stimulating factor production
regulation of endothelial tube morphogenesis
positive regulation of cardiac muscle cell differentiation
regulation of interleukin-12 secretion
transcription, DNA-templated
regulation of transcription, DNA-templated
anatomical structure morphogenesis
embryo development
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