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Invitrogen
MAD3 Recombinant Rabbit Monoclonal Antibody (8M7B3)
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MAD3 Antibody (MA5-38011) in WB
Western blot analysis of MAD3 in extracts of various cell lines. Samples were incubated with MAD3 Monoclonal antibody (Product # MA5-38011) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38011
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8M7B3
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 100-190 of human MAD3/MXD3 (Q9BW11)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.46 mg/mL
规格
46 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: A-549, DU145, Jurkat
Immunogen sequence: RRARMHIQKL EDQEQRARQL KERLRSKQQS LQRQLEQLRG LAGAAERERL RADSLDSSGL SSERSDSDQE ELEVDVESLV FGGEAELLRG F
靶标信息
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bHLHc13; Class C basic helix-loop-helix protein 13; FLJ35523; Max dimerization protein 3; Max dimerizer 3; Max-associated protein 3; Max-interacting transcriptional repressor MAD3; MGC2383; Myx
基因别名: BHLHC13; MAD3; MXD3
Entrez Gene ID: (Human) 83463
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