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Invitrogen
NEK6 Recombinant Rabbit Monoclonal Antibody (1V1X8)
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NEK6 Antibody (MA5-38077) in IHC (P)
Immunohistochemistry analysis of NEK6 in paraffin-embedded rat kidney. Samples were incubated with NEK6 Monoclonal antibody (Product # MA5-38077) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38077
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1V1X8
抗原
Recombinant protein (or fragment)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.8 mg/mL
规格
80 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: 293T, K-562, Mouse lung, Mouse brain, Rat brain
Immunogen sequence: ETTAAHSLVG TPYYMSPERI HENGYNFKSD IWSLGCLLYE MAALQSPFYG DKMNLFSLCQ KIEQCDYPPL PGEHYSEKLR ELVSMCICPD PHQRPDIGYV H
靶标信息
NEK6 kinase is a member of the NEK family. NEK6 is a serine/threonine kinase that controls the initiation of mitosis and is required for the metaphase-anaphase transition. The Aspergillus nidulans 'never in mitosis A' (NIMA) gene encodes a serine/threonine kinase that controls initiation of mitosis. NIMA-related kinases (NEKs) are a group of protein kinases that are homologous to NIMA. Evidence suggests that NEKs perform functions similar to those of NIMA. NEK6 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NEK6; Nek6; protein kinase; Never in mitosis A-related kinase 6; NIMA (never in mitosis gene a)-related expressed kinase 6; NIMA (never in mitosis gene a)-related kinase 6; NIMA-related expressed kinase 6; NimA-related protein kinase 6; Protein kinase SID6-1512; putative serine-threonine protein kinase; RP11-101K10.6; Serine/threonine-protein kinase Nek6; SID; unnamed protein product
基因别名: 1300007C09Rik; NEK6; SID6-1512
Entrez Gene ID: (Human) 10783, (Mouse) 59126, (Rat) 360161
protein phosphorylation
chromosome segregation
signal transduction
peptidyl-serine phosphorylation
regulation of mitotic metaphase/anaphase transition
protein autophosphorylation
mitotic spindle organization
mitotic nuclear envelope disassembly
regulation of mitotic cell cycle
regulation of chromosome organization
positive regulation of I-kappaB kinase/NF-kappaB signaling
spindle assembly
regulation of cellular senescence
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