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Invitrogen
RAD50 Monoclonal Antibody (3D2G10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-38619
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
3D2G10
抗原
Purified recombinant fragment of human RAD50 (aa: 228-359) expressed in E. Coli.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This antibody has been tested in indirect ELISA.
靶标信息
Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA repair protein RAD50; hRAD50; hsRAD50; RAD50 2; RAD50 PEN; RAD50-2; RAD50-3
基因别名: RAD50
UniProt ID: (Rat) Q9JIL8
Entrez Gene ID: (Rat) 64012
regulation of mitotic recombination
telomere maintenance
DNA catabolic process, endonucleolytic
DNA repair
double-strand break repair
DNA recombination
cellular response to DNA damage stimulus
telomere maintenance via telomerase
reciprocal meiotic recombination
regulation of mitotic cell cycle
positive regulation of protein autophosphorylation
DNA duplex unwinding
positive regulation of kinase activity
negative regulation of viral entry into host cell
chromosome organization
protein heterooligomerization
chromosome organization involved in meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
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