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Invitrogen
Histone H2A.Z Recombinant Rabbit Monoclonal Antibody (ST46-09)
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FIGURE: 1 / 5
Histone H2A.Z Antibody (MA5-41132) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of Histone-H2A.Z in Hela cells (green). Formalin fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 10 minutes at room temperature and blocked with 1% Blocker BSA for 15 minutes at room temperature. Cells were probed with Histone H2A.Z Recombinant Monoclonal Antibody (Product # MA5-41132) at a dilution of 1:50 for 1 hour at room temperature, wash... View More
Product Details
MA5-41132
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ST46-09
Immunogen
Synthetic peptide within human Histone H2AZ aa 1-50.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is predicted to work in Western Blot at a dilution of 1:500-1:1,000.
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 11ac; H2A histone family member V; H2A histone family member Z; H2A.F/Z; H2A.Z variant histone 2; H2A.ZK5; H2A.ZK5ac; H2A/z; H2AFZ; H2AFZac; H2AZ histone; H2AZK11ac; H2AZK7ac; histone (H2A.Z); histone H2A.F/Z; Histone H2A.V; Histone H2A.Z; purine-rich binding element protein B; unnamed protein product
Gene Aliases: C530002L11Rik; H2A.Z; H2A.Z-1; H2A.Z-2; H2A/z; H2AFV; H2AFZ; H2AV; H2AZ; H2AZ1; H2AZ2
UniProt ID: (Human) P0C0S5, (Human) Q71UI9, (Mouse) Q3THW5, (Mouse) P0C0S6, (Rat) P0C0S7
Entrez Gene ID: (Human) 3015, (Human) 94239, (Mouse) 77605, (Mouse) 51788, (Rat) 58940
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
DNA binding
protein binding
structural constituent of chromatin
chromatin DNA binding
nucleosomal DNA binding
protein heterodimerization activity
binding, bridging
RNA polymerase II distal enhancer sequence-specific DNA binding
molecular_function
histone
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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