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Invitrogen
WNT2B Recombinant Rabbit Monoclonal Antibody (JB48-34)
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FIGURE: 1 / 5
WNT2B Antibody (MA5-42480) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of Wnt2b in SHSY-5Y cells (green) using WNT2B Recombinant Monoclonal Antibody (Product # MA5-42480). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-42480
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JB48-34
Immunogen
Recombinant protein within Human Wnt2b aa 175-355 .
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: SiHa, Hela, LOVO, SHSY-5Y, human kidney tissue, mouse kidney tissue, rat testis tissue.
Subcellular Location: Secreted. Extracellular region.
Target Information
WNT2B is a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. It may play a role in human development as well as human carcinogenesis. Two alternatively spliced transcript variants exist.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein Wnt-13; Protein Wnt-2b; wingless related MMTV integration site 2b; wingless-type MMTV integration site 2B; wnt-13
Gene Aliases: WNT13; WNT2B
UniProt ID: (Mouse) O70283
Entrez Gene ID: (Mouse) 22414, (Rat) 116466
signal transduction
cell-cell signaling
multicellular organism development
cellular response to starvation
organ morphogenesis
Wnt signaling pathway
neuron differentiation
cell fate commitment
canonical Wnt signaling pathway
lung induction
mesenchymal-epithelial cell signaling
hematopoietic stem cell proliferation
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
chondrocyte differentiation
biological_process
male gonad development
forebrain regionalization
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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