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Invitrogen
Serglycin Monoclonal Antibody (C1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-43587
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
C1
抗原
Asp119-Gly148 (Accession P10124), with N-terminal His Tag
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
20 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chondroitin sulfate proteoglycan core protein; Cytolytic granule proteoglycan core protein; Hematopoietic proteoglycan core protein; P.PG; PG19 core protein; Platelet proteoglycan core protein; Proteoglycan 10K core protein; proteoglycan peptide core protein; Secretory granule proteoglycan core protein; Serglycin
基因别名: Pgsg; PRG; PRG1; SRGN
UniProt ID: (Rat) P04917
Entrez Gene ID: (Rat) 56782
biological_process
granzyme-mediated apoptotic signaling pathway
protein processing
negative regulation of bone mineralization
biomineral tissue development
mast cell secretory granule organization
T cell secretory granule organization
maintenance of protease location in mast cell secretory granule
maintenance of granzyme B location in T cell secretory granule
negative regulation of cytokine secretion
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