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Invitrogen
PSMC3 Monoclonal Antibody (4D3)
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FIGURE: 1 / 6
PSMC3 Antibody (MA5-49297) in ICC/IF
Immunocytochemistry analysis of PSMC3 in MCF-7 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent for 15 mins. The cells were blocked with 10% goat serum. Samples were then incubated in PSMC3 Monoclonal antibody (Product # MA5-49297) using a dilution of 5 μg/mL. DyLight®488 Conjugated Goat Anti-Mouse IgG was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate fo... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-49297
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
4D3
Immunogen
E.coli-derived human TBP-1/PSMC3 recombinant protein (Position: M1-A439).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
no preservative
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Adding 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
Positive Control - WB: human HEK293 whole cell, human Hela whole cell, human HepG2 whole cell, human PC-3 whole cell, rat stomach tissue, rat kidney tissue, mouse stomach tissue, mouse kidney tissue. IHC: human liver cancer tissue, human colonic adenocarcinoma tissue. ICC/IF: MCF-7 cell. Flow: U937 cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene encodes a WASP interacting protein (WIP)-related protein. It has been shown that this protein has a role in the WASP-mediated organization of the actin cytoskeleton and that this protein is a potential link between the activated platelet-derived growth factor receptor and the actin polymerization machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 26S protease regulatory subunit 6A; 26S proteasome AAA-ATPase subunit RPT5; human immunodeficiency virus tat transactivator binding protein-1; MGC8487; proteasome (prosome, macropain) 26S subunit, ATPase 3; proteasome (prosome, macropain) 26S subunit, ATPase, 3; proteasome 26S subunit ATPase 3; proteasome subunit P50; PSMC3; rpt5; spermatogenic cell/sperm-associated TAT-binding protein homolog SATA; Tat binding protein 1; tat binding protein-1 (tbp-1); TAT-binding protein 1; TBP-1; testicular secretory protein Li 42; unnamed protein product
Gene Aliases: DCIDP; EBNDS; RPT5; TBP-1; TBP1
UniProt ID: (Human) P17980, (Mouse) O88685, (Rat) Q63569
Entrez Gene ID: (Human) 5702, (Mouse) 19182, (Rat) 29677
response to oxidative stress
proteasomal protein catabolic process
proteasome-mediated ubiquitin-dependent protein catabolic process
modulation by host of viral transcription
positive regulation of transcription from RNA polymerase II promoter
regulation of proteasomal protein catabolic process
cellular response to type I interferon
positive regulation of proteasomal protein catabolic process
blastocyst development
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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