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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
KLRG1 (Killer cell lectin-like receptor G1, MAFA, 2F1-Ag) is a homodimeric member of the lectin-like type 2 transmembrane receptor family whose members contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. These ITIMs interact with the SH2 domains of protein phosphatases such as SHP-1. KLRG1 is an inhibitory receptor that is expressed on natural killer (NK) cells and certain T cells. NK cells are involved in the lysis of tumor cells and virus-infected cells, and mediate humoral and cell-mediated immune responses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-type lectin domain family 15 member A; ITIM-containing receptor MAFA-L; Killer cell lectin-like receptor subfamily G member 1; MAFA-like receptor; Mast cell function-associated antigen; natural killer cell receptor
基因别名: CLEC15A; KLRG1; MAFA; MAFAL
Entrez Gene ID: (Human) 10219