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Invitrogen
DYNLL1 Recombinant Rabbit Monoclonal Antibody (20A1)
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DYNLL1 Antibody (MA5-50177) in IHC (P)
Immunohistochemistry analysis with a DYNLL1 monoclonal antibody (Product # MA5-50177) using a dilution of 1:50 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30 min at RT. Then primary antibody (1% BSA) was incub... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-50177
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
20A1
抗原
A synthesized peptide derived from Human DYNLL1
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.77 mg/mL
规格
77 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1, 200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. DYNLL1 is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 8 kDa dynein light chain; DLC1DNCLC1; DLC8; DLC8MGC126137; DNCL1MGC126138; Dynein light chain 1, cytoplasmic; Dynein light chain LC8-type 1; H LC8; LC8-type 1; MGC126137; MGC126138; PIN; PINLC8a; Protein inhibitor of neuronal nitric oxide synthase
基因别名: DLC1; DNCL1; DNCLC1; DYNLL1; HDLC1
Entrez Gene ID: (Human) 8655
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
