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Invitrogen
ProANP Monoclonal Antibody (C6)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-51085
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
C6
抗原
Recombinant Human NT-ProANP protein, Ala25-Arg123 (Accession #P01160)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
200 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% Proclin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ANPRC; atrial natriuretic factor; Atrial natriuretic factor prohormone; atrial natriuretic peptide; Atrial natriuretic peptide prohormone; Atrial natriuretic peptide receptor 3; Atriopeptigen; Cardiodilatin; CDD; Natriuretic peptide precursor A (pronatriodilatin, also Anf, Pnd); natriuretic peptide precursor type A; Natriuretic peptides A; NPR3; preproANF; preproANP; preproCDD-ANF; prepronatriodilatin; proANF
基因别名: ANF; ANP; NPPA; PND; RATANF
UniProt ID: (Rat) P01161
Entrez Gene ID: (Rat) 24602
response to hypoxia
negative regulation of systemic arterial blood pressure
cGMP biosynthetic process
receptor guanylyl cyclase signaling pathway
neuropeptide signaling pathway
heart development
female pregnancy
regulation of blood pressure
positive regulation of heart rate
cardiac muscle hypertrophy in response to stress
negative regulation of cell growth
response to insulin
regulation of body fluid levels
regulation of blood vessel size
multicellular organismal water homeostasis
regulation of atrial cardiac muscle cell membrane repolarization
positive regulation of cardiac muscle contraction
cellular response to mechanical stimulus
regulation of high voltage-gated calcium channel activity
positive regulation of delayed rectifier potassium channel activity
regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
positive regulation of potassium ion export across plasma membrane
negative regulation of collecting lymphatic vessel constriction
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
