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Invitrogen
SEMA3A Recombinant Rabbit Monoclonal Antibody (7M10D0)
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SEMA3A Antibody (MA5-51333) in WB
Western blot analysis of SEMA3A in various lysates. Samples were incubated with SEMA3A Recombinant monoclonal antibody (Product # MA5-51333) using a dilution of 1:20,000 followed by HRP Goat Anti-Rabbit IgG (H+L) secondary antibody at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-51333
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
7M10D0
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 582-771 of human Semaphorin 3A (NP_006071.1).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.055 mg/mL
规格
5.5 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 0.05% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ERIIYGVENS STFLECSPKS QRALVYWQFQ RRNEERKEEI RVDDHIIRTD QGLLLRSLQQ KDSGNYLCHA VEHGFIQTLL KVTLEVIDTE HLEELLHKDD DGDGSKTKEM SNSMTPSQKV WYRDFMQLIN HPNLNTMDEF CEQVWKRDRK QRRQRPGHTP GNSNKWKHLQ ENKKGRNRRT HEFERAPRSV
靶标信息
This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: collapsin-1; MGC133243; Sema D; Sema III; Semaphorin III; Semaphorin-3A; Semaphorin-D
基因别名: coll-1; Hsema-I; SEMA1; SEMA3A; SEMAD; SemD
UniProt ID: (Mouse) O08665
Entrez Gene ID: (Mouse) 20346
neuron migration
regulation of heart rate
apoptotic process
multicellular organism development
nervous system development
axon guidance
axonal fasciculation
motor neuron axon guidance
negative regulation of epithelial cell migration
facial nerve structural organization
trigeminal nerve structural organization
nerve development
olfactory bulb development
branchiomotor neuron axon guidance
gonadotrophin-releasing hormone neuronal migration to the hypothalamus
cell differentiation
negative regulation of axon extension
ventral trunk neural crest cell migration
dendrite morphogenesis
regulation of axon extension involved in axon guidance
negative regulation of axon extension involved in axon guidance
axon extension involved in axon guidance
negative chemotaxis
axonogenesis involved in innervation
dichotomous subdivision of terminal units involved in salivary gland branching
sympathetic ganglion development
trigeminal ganglion development
semaphorin-plexin signaling pathway
sympathetic neuron projection extension
sympathetic neuron projection guidance
neural crest cell migration involved in autonomic nervous system development
semaphorin-plexin signaling pathway involved in neuron projection guidance
semaphorin-plexin signaling pathway involved in axon guidance
neural crest cell migration involved in sympathetic nervous system development
facioacoustic ganglion development
positive regulation of male gonad development
positive regulation of neuron migration
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