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Invitrogen
CEACAM6 Recombinant Rabbit Monoclonal Antibody (111)
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Product Details
MA5-52256
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
111
Immunogen
Recombinant Human CEACAM6/CD66c protein (1-320).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Cross-reactivity in ELISA with Human CEACAM1. No cross-reactivity in ELISA with Human CEACAM5.
Target Information
CEA Cell Adhesion Molecule 6 (CEACAM6) belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. CEACAM6 affects the sensitivity of tumor cells to adenovirus infection. The acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BGP; BGP-1; carcinoembryonic antigen related cell adhesion molecule 6; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66c; CD66d; CD66e; CEA; CEA cell adhesion molecule 6; CEACAM-1; CEACAM-3; CEACAM-5; CEACAM-6; Cell adhesion molecule CEACAM6; CGM1; Cluster of Differentiation 66c; Non-specific crossreacting antigen; nonspecific crossreacting antigen precursor; Normal cross-reacting antigen; ORF1; ORF2; pan CEACAM; unnamed protein product
Gene Aliases: CD66c; CEACAM6; CEAL; NCA; NCA-50/90
UniProt ID: (Human) P40199
Entrez Gene ID: (Human) 4680
apoptotic process
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
positive regulation of cell proliferation
positive regulation of cell migration
positive regulation of heterotypic cell-cell adhesion
positive regulation of endothelial cell-matrix adhesion via fibronectin
negative regulation of anoikis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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