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Invitrogen
CHM Recombinant Rabbit Monoclonal Antibody (23GB3065)
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图: 1 / 3
CHM Antibody (MA5-52540) in ICC/IF
Immunocytochemistry analysis of CHM in HepG2 cells. Sample was incubated with CHM monoclonal (Product # MA5-52540) antibody at a dilution of 1:1,000, followed by DAPI and Alexa Fluor 647. Protein abundance based on laser intensity and smart gain: Medium. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA5-52540
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB3065
抗原
A synthesized peptide derived from CHM (49-81AA).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
40 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: choroideraemia protein homolog; Choroideremia protein; Choroideremia protein homolog; choroidermia; Rab escort protein 1; Rab proteins geranylgeranyltransferase component A 1; REP-1; TCD protein
基因别名: CHM; Rep-1; REP1; TCD
UniProt ID: (Rat) P37727
Entrez Gene ID: (Mouse) 12662, (Rat) 24942
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